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One challenge with using troponins to diagnose acute myocardial infarctions is troponins can be elevated in other disorders as well.[sixty one] Everything that causes damage to cardiac muscle mass can cause troponin to spill into circulation. The most common explanation for injury is oxygen source and demand mismatch, seen in acute myocardial infarction.

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The theory of your cTnT measurement is definitely an ELISA just one-step sandwich assay making use of streptavidin technological innovation and electrochemiluminescence detection.[fifty four] In the initial incubation action (immunological response), the cTnT in the sample reacts by using a biotinylated mouse monoclonal anti-cTnT antibody and a monoclonal cTnT-certain antibody labeled with a ruthenium intricate to variety a sandwich complicated.

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